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Incidence et prévalence des complications oculaires du diabète en France entre 2008 et 2018- Etude LANDSCAPE

LANDSCAPE aimed to estimate the incidence and prevalence of DME and PDR in the French population between 2008 and 2018.

This population-based study used retrospective longitudinal healthcare consumption data from the National Health DataSystem (Système National des Données de Santé [SNDS]).Our algorithm identified people with DME and PDR combining diagnoses or reimbursement of specific treatments. We identified DME and PDR patients using detailed inclusion and exclusion criteria based on SNDS data on age, diagnosis, healthcare consumption (and alternate ocular diagnoses). We estimated incidence and prevalence, based on the age-matched population with diabetes in France.

We identified 53,584 DME patients and 127,273 PDR patients between 2008 and 2018, and 11,901 DME and 11,996 PDR new incident patients in 2018. With a 2018 adult diabetic French population identified of 3,192,475, the 2018 incidence of DME was 0.373% in diabetics and prevalence was 1.437%. DME incidence and prevalence increased with age, the highest rate of 0.561% was observed in diabetics aged 70-74 years.

In 2018, the incidence of PDR was 0.312% in diabetics and prevalence was 2.700%. PDR prevalence was not associated with age. In people with diabetes, we observed two peaks in PDR incidence around ages 30-39 years and 65-74 years.

The incidence of DME rose from 2012-2018 whereas incidence of PDR remained stable from 2008 to 2018. No variation was observed according to residential zone or proximity to primary or ophthalmology care.

We provided exhaustive nationwide data on incidence and prevalence of diabetic ocular complications in France over a 10-year period.

These results can help plan resource allocation to ensure adequate patient care in the coming years, when diabetes is predicted to rise.